Toki Tori
Take your everyday platform-puzzler - trying to get a little guy through a maze of obstacles and enemies toward some goal(s) - and add wacky sound effects, shiny graphics, and super-cool items, and you're looking at Toki Tori.
The puzzles are pretty good so far (having completed the first of four(?) worlds, each of which I guess has 10 levels), and the nifty point-and-pathfind remote control scheme works surprisingly well, but by far the coolest part of Toki Tori is the item system. The first item in the game is a bridge, which you can build to cross small gaps. The second item is a teleporter, which you can use to instantly move two spaces in a given direction. The third item is an ice gun to freeze enemies. I can only assume the items will continue to become even more awesome at a ridiculous pace.
Progress: Finished Forest Falls world